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Cat. No.: HY-168904

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BI-1942

BI-1942, a chemical probe, is a chymase inhibitor and has an IC₅₀ of 0.4 nM for human chymase. BI-1942 can be used in the research of ophthalmic diseases.

For research use only. We do not sell to patients.

The BI-1942 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.

CAS No.: 1236524-95-0
Formula: C₂₄H₂₆N₄O₄
Molecular Weight:434.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

BI-1942 Chemical Structure

CAS No.: 1236524-95-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BI-1942, a chemical probe, is a chymase inhibitor and has an IC₅₀ of 0.4 nM for human chymase. BI-1942 can be used in the research of ophthalmic diseases^[1].

Chemical Information

CAS No. 1236524-95-0
Molecular Weight 434.49
Formula C₂₄H₂₆N₄O₄
SMILES

CN1C2=CC(C)=CC(C)=C2C(CN3C4=CC=CN=C4C(N(C3=O)[C@H](CC)CC(O)=O)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Abbe P, et al. Metadata analysis of Boehringer Ingelheim's opnMe database reveals the potential of BI-1942, a chymase inhibitor, for ophthalmic indications repurposing. Investigative Ophthalmology & Visual Science, 2024, 65(7): 6126-6126.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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