CDK8-IN-19
CDK8-IN-19 (Compound 3d) is a CDK8 inhibitor with an IC50 of 25.08 nM. CDK8-IN-19 has a broad-spectrum anticancer activity, such as leukemia, melanoma and breast cancer, without significant cytotoxic effect on the normal Vero cells (mean IC50s of 2.87, 3.65, 3.79 and 45.48 μM, respectively).
For research use only. We do not sell to patients.
- Formula: C17H11Cl2N3OS2
- Molecular Weight:408.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK8/cyclin C 25.08 nM (IC50) |
PI3Kα 86.62 nM (IC50) |
CDK2/CycA2 1.13 μM (IC50) |
Chemical Information
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Molecular Weight 408.32
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Formula C17H11Cl2N3OS2
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SMILES
S=C(NC1=CC=C(Cl)C=C1Cl)NC(S/C2=C/C3=CC=CC=C3)=NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDK8-IN-19 Related Classifications
HY-176282 Related Classifications
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