Gdf10 - growth differentiation factor 10 Gene

Also Known as Bmp3b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14560

Summary

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family Transcription Factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein has been shown to promote neural repair after stroke and may act as a tumor suppressor. [provided by RefSeq, Jul 2016]

Gdf10 Products (1)

mRNA Protein Name
NM_145741.3 NP_665684.2 growth/differentiation factor 10 preproprotein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in fat cell differentiation IMP
IMP: Inferred from mutant phenotype
21712809 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth/differentiation factor 10

  • bone morphogenetic protein 3b

Recombinant Gdf10 Proteins

Cat. No. Product Name Accession Purity
HY-P75788 BMP-3B/GDF10 Protein, Mouse (HEK293, Fc) P97737 (Q367-R476) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05350 GDF10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18389 Gdf10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24870 Gdf10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gdf10 NCBI NCBI:2662