Kif2c - kinesin family member 2C Gene

Also Known as MCAK; ESTM5; Knsl6; 4930402F02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73804

Summary

Predicted to enable ATP hydrolysis activity; microtubule motor activity; and microtubule plus-end binding activity. Predicted to be involved in several processes, including attachment of mitotic spindle microtubules to kinetochore; microtubule Cytoskeleton organization; and regulation of chromosome segregation. Predicted to act upstream of or within cell division and chromosome segregation. Located in chromosome, centromeric region. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human KIF2C (Kinesin family member 2C). [provided by Alliance of Genome Resources, Apr 2022]

Kif2c Products (4)

mRNA Protein Name
NM_001290662.1 NP_001277591.1 kinesin-like protein KIF2C isoform 2
NM_134471.4 NP_608301.3 kinesin-like protein KIF2C isoform 1
NM_001290662.1 NP_001277591.1 kinesin-like protein KIF2C isoform 2
NM_134471.4 NP_608301.3 kinesin-like protein KIF2C isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in postsynaptic cytoskeleton organization IDA
IDA: Inferred from direct assay
35138249 MGI
involved in postsynaptic cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
35138249 MGI
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
35138249 MGI
involved in regulation of neurotransmitter receptor localization to postsynaptic specialization membrane IMP
IMP: Inferred from mutant phenotype
35138249 MGI
Cellular Component GO Annotation Evidence References Source
located in chromosome, centromeric region IDA
IDA: Inferred from direct assay
19283064 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
35138249 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
35138249 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
35138249 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
35138249 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
35138249 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
35138249 MGI
is active in presynapse IEP
IEP: Inferred from expression pattern
35138249 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kinesin-like protein KIF2C

  • kinesin-like 6

  • mitotic centromere-associated kinesin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-173522 KIF2C-IN-1 98.08% Unkown
HY-RS07284 KIF2C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20434 Kif2c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26943 Kif2c Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kif2c NCBI NCBI:11004