2. Gene
  3. KIF2C - kinesin family member 2C Gene

KIF2C - kinesin family member 2C Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as MCAK; CT139; KNSL6

Gene ID: 11004 | Gene type: protein coding

About KIF2C

Cytogenetic location: 1p34.1 Genomic coordinates (GRCh38): 1:44,739,837-44,767,767 (from NCBI)

This gene has 8 transcripts (splice variants), 127 orthologues and 41 paralogues. Biased expression in testis (RPKM 39.1), bone marrow (RPKM 9.5) and 6 other tissues.

Summary

This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

KIF2C Products(4)

mRNA Protein Name
NM_001297655.2 NP_001284584.1 kinesin-like protein KIF2C isoform 2
NM_001297656.2 NP_001284585.1 kinesin-like protein KIF2C isoform 3
NM_001297657.2 NP_001284586.1 kinesin-like protein KIF2C isoform 4
NM_006845.4 NP_006836.2 kinesin-like protein KIF2C isoform 1

KIF2C Protein Structure

Kinesin

Kinesin: Kinesin motor domain (264 - 587)

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  • 600
  • 725 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIF2C

kinesin-like protein 6

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07284 KIF2C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus KIF2C VGNC VGNC:30601
Felis catus KIF2C VGNC VGNC:67974
Mus musculus KIF2C MGD MGI:1921054
Macaca mulatta KIF2C VGNC VGNC:74034
Rattus norvegicus KIF2C RGD RGD:620239
Canis familiaris KIF2C VGNC VGNC:42403