U-56324
U-56324 is an orally effective ATP-sensitive potassium channel (KATP) inhibitor with an EC50 of 233 µM. U-56324 inhibits KATP channel activity in the plasma membrane of pancreatic B cells in a concentration-dependent and reversible manner, without affecting single-channel conductance. U-56324 can be used for research on type 2 diabetes and insulin secretion.
For research use only. We do not sell to patients.
- CAS No.: 75587-96-1
- Formula: C11H15NO3
- Molecular Weight:209.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
KATP 233 μM (EC50) |
In Vitro
U-56324 (5-5000 μM; <10 seconds) directly, reversibly, and concentration-dependently inhibits K(ATP) channel activity in excised outside-out patches from mouse pancreatic B-cells with an EC50 of 233 μM, without affecting single channel conductance[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 75587-96-1
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Molecular Weight 209.24
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Formula C11H15NO3
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SMILES
O=C(C1=CC=C(CC(C)(C)C)NC1=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
U-56324 Related Classifications
HY-187737 Related Classifications
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