DL-Buthionine-(S,R)-sulfoximine hydrochloride (Standard)
DL-Buthionine-(S,R)-sulfoximine (hydrochloride) (Standard) is the analytical standard of DL-Buthionine-(S,R)-sulfoximine (hydrochloride). This product is intended for research and analytical applications. DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
For research use only. We do not sell to patients.
- Purity : 98%
- Formula: C8H19ClN2O3S
- Molecular Weight:258.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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Molecular Weight 258.77
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Formula C8H19ClN2O3S
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SMILES
OC(C(N)CCS(CCCC)(=N)=O)=O.[H]Cl
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Synonyms
Buthionine sulfoximine hydrochloride (Standard); BSO hydrochloride (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Griffith OW, et al. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). J Biol Chem. 1979 Aug 25;254(16):7558-60. [Content Brief]
[2]. Vanhoefer U, et al. d,l-buthionine-(S,R)-sulfoximine potentiates in vivo the therapeutic efficacy of doxorubicin against multidrug resistance protein-expressing tumors. Clin Cancer Res. 1996 Dec;2(12):1961-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)