DMS-612
DMS-612 (NSC-281612) is an alkylating agent with anti-renal cell carcinoma activity. DMS-612 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 56967-08-9
- Formula: C14H21NO7S2
- Molecular Weight:379.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DMS-612 (1000 ng/mL, 0-24 h) The IC50 values of 786-0, ACHN, SN12K1, AKI-1, and A498 cells are 0.267, 0.263, 0.790, 0.202, 0.0463 μg/mL, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 56967-08-9
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Molecular Weight 379.45
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Formula C14H21NO7S2
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SMILES
O=CC1=CC=C(N(CCOS(=O)(C)=O)CCOS(=O)(C)=O)C=C1C
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Synonyms
NSC-281612
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Parise RA, et al. Formation of active products of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) in human blood and plasma and their activity against renal cell carcinoma lines. Cancer Chemother Pharmacol. 2013 Jan;71(1):73-83. doi: 10.1007/s00280-012-1980-1. Epub 2012 Oct 5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DMS-612 Related Classifications
HY-19412 Related Classifications
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