DPP-4/GPR119 modulator 2
DPP-4/GPR119 modulator 2 (Compound 20i) is a dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist with an IC50 of 0.22 μM for DPP-IV and an EC50 of 0.95 μM for GPR119. DPP-4/GPR119 modulator 2 can be used for diabetes research. DPP-4/GPR119 modulator 2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- CAS No.: 2010927-65-6
- Formula: C30H40N8O3
- Molecular Weight:560.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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DPP-4 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
0.95 μM
Compound: 20i
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Agonist activity at CREB-LBD and GAL4-DBD fused human GPR119 expressed in HEK293 cells by luciferase reporter gene assay
Agonist activity at CREB-LBD and GAL4-DBD fused human GPR119 expressed in HEK293 cells by luciferase reporter gene assay
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[PMID: 27560285] |
Chemical Information
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CAS No. 2010927-65-6
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Molecular Weight 560.69
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Formula C30H40N8O3
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SMILES
CC#CCN1C(N2CCC[C@H](C2)N)=NC3=C1C(N(C(N3C)=O)CCCN4CCC(CC4)C(NC5=CC=CC=C5)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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