2. Anti-infection
  3. Filovirus
  4. EBOV-GP-IN-1

EBOV-GP-IN-1 (Compound 28) is a potent Ebola entry inhibitor with an IC50 of 0.05 μM against Ebola virus envelope glycoprotein (EBOV-GP).

For research use only. We do not sell to patients.

EBOV-GP-IN-1 Chemical Structure

EBOV-GP-IN-1 Chemical Structure

CAS No. : 3032283-85-2

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EBOV-GP-IN-1 Related Antibodies

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Description

EBOV-GP-IN-1 (Compound 28) is a potent Ebola entry inhibitor with an IC50 of 0.05 μM against Ebola virus envelope glycoprotein (EBOV-GP)[1].

IC50 & Target

IC50: 0.05 μM (EBOV-GP), 3.02 μM (VSV-G)[1]
In Vitro

EBOV-GP-IN-1 (Compound 28) (0-80 μM, 2 days) shows cytotoxicity with a CC50 of 5.10 ± 1.56 μM for Huh7 cells in pseudotyped virus assay[1].
EBOV-GP-IN-1 exhibits remarkable selectivity between EBOV-GP and VSV-G (vesicular stomatitis virus glycoprotein) (Spec. Index = 58)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EBOV-GP-IN-1 Related Antibodies
Molecular Weight

450.06

Formula

C25H40ClN3O2
CAS No.
SMILES

O=C([C@H]1N(C[C@@H](O)CN[C@H](C2=CC=C(Cl)C=C2)C)C[C@@]3([H])CCCC[C@@]3([H])C1)NC(C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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EBOV-GP-IN-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EBOV-GP-IN-13032283-85-2FilovirusHuh7Ebola virusEBOV-GPenvelope glycoproteinInhibitorinhibitorinhibit

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EBOV-GP-IN-1
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HY-150756
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