EBOV-GP-IN-1
EBOV-GP-IN-1 (Compound 28) is a potent Ebola entry inhibitor with an IC50 of 0.05 μM against Ebola virus envelope glycoprotein (EBOV-GP).
For research use only. We do not sell to patients.
- CAS No.: 3032283-85-2
- Formula: C25H40ClN3O2
- Molecular Weight:450.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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EBOV |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
5.1 μM
Compound: 28
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Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability by cellular ATP method
Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability by cellular ATP method
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[PMID: 35872393] |
EBOV-GP-IN-1 (Compound 28) (0-80 μM, 2 days) shows cytotoxicity with a CC50 of 5.10 ± 1.56 μM for Huh7 cells in pseudotyped virus assay[1].
EBOV-GP-IN-1 exhibits remarkable selectivity between EBOV-GP and VSV-G (vesicular stomatitis virus glycoprotein) (Spec. Index = 58)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3032283-85-2
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Molecular Weight 450.06
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Formula C25H40ClN3O2
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SMILES
O=C([C@H]1N(C[C@@H](O)CN[C@H](C2=CC=C(Cl)C=C2)C)C[C@@]3([H])CCCC[C@@]3([H])C1)NC(C)(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EBOV-GP-IN-1 Related Classifications
HY-150756 Related Classifications
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