2. Metabolic Enzyme/Protease Anti-infection
  3. MetAP Bacterial
  4. ecMetAP-IN-1

ecMetAP-IN-1 is an inhibitor of E. coli methionine aminopeptidase (ecMetAP) with an IC50 of 2.086 μM. ecMetAP-IN-1 is applicable to research related to bacterial infections caused by E. coli.

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ecMetAP-IN-1

ecMetAP-IN-1 화학구조

CAS No. : 7471-12-7

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg   견적 받기  
10 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

ecMetAP-IN-1 Related Antibodies

Top Publications Citing Use of Products

View All MetAP Isoform Specific Products:

View All Isoforms
MetAP1 MetAP2

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

ecMetAP-IN-1 is an inhibitor of E. coli methionine aminopeptidase (ecMetAP) with an IC50 of 2.086 μM. ecMetAP-IN-1 is applicable to research related to bacterial infections caused by E. coli[1].

Cellular Effect
Cell Line Type Value Description References
Sf9 IC50
7.7 μM
Compound: 16
Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells
Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells
[PMID: 20621724]
In Vitro

ecMetAP-IN-1 (Compound 17) (45 min) inhibits CoII-Loaded Escherichia coli methionine aminopeptidase with an IC50 value of 2.086 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ecMetAP-IN-1 Related Antibodies
분자량

209.25

화학식

C13H11N3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=CC=C2N=C(C3=NC=CC=C3)NC2=C1
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

DMSO : 100 mg/mL (477.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7790 mL 23.8949 mL 47.7897 mL
5 mM 0.9558 mL 4.7790 mL 9.5579 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.7790 mL 23.8949 mL 47.7897 mL 119.4743 mL
5 mM 0.9558 mL 4.7790 mL 9.5579 mL 23.8949 mL
10 mM 0.4779 mL 2.3895 mL 4.7790 mL 11.9474 mL
15 mM 0.3186 mL 1.5930 mL 3.1860 mL 7.9650 mL
20 mM 0.2389 mL 1.1947 mL 2.3895 mL 5.9737 mL
25 mM 0.1912 mL 0.9558 mL 1.9116 mL 4.7790 mL
30 mM 0.1593 mL 0.7965 mL 1.5930 mL 3.9825 mL
40 mM 0.1195 mL 0.5974 mL 1.1947 mL 2.9869 mL
50 mM 0.0956 mL 0.4779 mL 0.9558 mL 2.3895 mL
60 mM 0.0796 mL 0.3982 mL 0.7965 mL 1.9912 mL
80 mM 0.0597 mL 0.2987 mL 0.5974 mL 1.4934 mL
100 mM 0.0478 mL 0.2389 mL 0.4779 mL 1.1947 mL
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ecMetAP-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ecMetAP-IN-17471-12-7MetAPBacterialMethionine AminopeptidaseEscherichia colimethionine aminopeptidasebacterial infectionInhibitorinhibitorinhibit

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상품명:
ecMetAP-IN-1
Cat. No.:
HY-148442
수량:
MCE Japan Authorized Agent:

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