ENPP3 Inhibitor 1

Cat. No.: HY-169804 Purity: 99.43%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

ENPP3 Inhibitor 1 is a selective inhibitor of ENPP3, with IC₅₀s of 0.15 µM (ENPP3) and 41.4 µM (ENPP1) respectively. ENPP3 Inhibitor 1 shows anti-tumor activities against breast cancer and cervical cancer.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

ENPP3 Inhibitor 1 화학구조

CAS No. : 2803505-90-8

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	견적 받기
200 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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View All Isoforms

PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

Biological Activity
순도&문서
References
고객리뷰

제품 설명

In Vitro

ENPP3 Inhibitor 1 (Compound 4t) (100 μM, 24 h) shows anti-tumor activities against human cancer cell lines MCF7, HeLa and human embryonic kidney cell lines HEK293, with the inhibition rate of 29.6%, 49.7% and 8.6%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

437.39

화학식

C₂₀H₁₄F₃NO₅S

CAS No.

2803505-90-8

Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=CC=C1)NC2=CC=C(C=C2)OS(=O)(C3=CC=C(C=C3)OC(F)(F)F)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : ≥ 116.67 mg/mL (266.74 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2863 mL	11.4314 mL	22.8629 mL
5 mM	0.4573 mL	2.2863 mL	4.5726 mL
10 mM	0.2286 mL	1.1431 mL	2.2863 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.43%

Select Batch:

Data Sheet (270 KB) SDS (251 KB)

COA (246 KB) HNMR (277 KB) LCMS (339 KB)

Handling Instructions (2659 KB)

References

[1]. Ullah, et al. Synthesis and Biological Evaluation of Arylamide Sulphonate Derivatives as Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 and -3 Inhibitors. ACS Omega. 2022, 7(30):26905-26918. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2863 mL	11.4314 mL	22.8629 mL	57.1572 mL
	5 mM	0.4573 mL	2.2863 mL	4.5726 mL	11.4314 mL
	10 mM	0.2286 mL	1.1431 mL	2.2863 mL	5.7157 mL
	15 mM	0.1524 mL	0.7621 mL	1.5242 mL	3.8105 mL
	20 mM	0.1143 mL	0.5716 mL	1.1431 mL	2.8579 mL
	25 mM	0.0915 mL	0.4573 mL	0.9145 mL	2.2863 mL
	30 mM	0.0762 mL	0.3810 mL	0.7621 mL	1.9052 mL
	40 mM	0.0572 mL	0.2858 mL	0.5716 mL	1.4289 mL
	50 mM	0.0457 mL	0.2286 mL	0.4573 mL	1.1431 mL
	60 mM	0.0381 mL	0.1905 mL	0.3810 mL	0.9526 mL
	80 mM	0.0286 mL	0.1429 mL	0.2858 mL	0.7145 mL
	100 mM	0.0229 mL	0.1143 mL	0.2286 mL	0.5716 mL