AM4299 A
AM4299 A is a thiol protease inhibitor with IC50 values of 73, 390 and 88 nM against Cathepsin B, Cathepsin L and Papain, respectively. AM4299 A shows low toxicity and favorable biosafety in mice. AM4299 A can be used in studies related to osteoporosis and parasitic diseases.
For research use only. We do not sell to patients.
- CAS No.: 160825-48-9
- Formula: C15H26N2O6
- Molecular Weight:330.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Cathepsin Isoforms
More
Biological Activity
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Cathepsin C 73 nM (IC50) |
cathepsin L 390 nM (IC50) |
papain 88 nM (IC50) |
AM4299 A specifically inhibits purified bovine spleen cathepsin B (IC50 = 7.3 × 10-8 M), human kidney cathepsin L (IC50 = 3.9 × 10-7 M), and Carica papaya papain (IC50 = 8.8 × 10-8 M), with no activity against bovine pancreas trypsin or α-chymotrypsin at concentrations up to 8.0 × 10-5 M[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 160825-48-9
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Molecular Weight 330.38
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Formula C15H26N2O6
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SMILES
C(N[C@H](C(NCCCCCO)=O)CC(C)C)(=O)C1C(C(O)=O)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AM4299 A Related Classifications
HY-187615 Related Classifications
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