Zavacorilant
Zavacorilant is capable of modulating glucocorticoid receptor (GR).
For research use only. We do not sell to patients.
- CAS No.: 1781245-13-3
- Formula: C25H26FN7O3S2
- Molecular Weight:555.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 1781245-13-3
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Molecular Weight 555.65
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Formula C25H26FN7O3S2
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SMILES
O=C(C1=CSC=N1)[C@@]23[C@](CCN(C3)S(=O)(C4=NN(N=C4)C(C)C)=O)([H])CC5=C(C=NN5C6=CC=C(C=C6)F)C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Zavacorilant Related Classifications
HY-139556 Related Classifications
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