2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. ADC Payload Topoisomerase
  4. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) is an exatecan (HY-13631) derivative that can be used as a payload in drug conjugates. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol has significant inhibitory activity against a variety of tumor cell lines.

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Exatecan-amide-bicyclo[1.1.1]pentan-1-ol

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol Estructura química

No. CAS : 2866299-06-9

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Exatecan-amide-bicyclo[1.1.1]pentan-1-ol Related Antibodies

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Descripciòn

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol (Compound 79) is an exatecan (HY-13631) derivative that can be used as a payload in drug conjugates. Exatecan-amide-bicyclo[1.1.1]pentan-1-ol has significant inhibitory activity against a variety of tumor cell lines[1].

IC50 & Target

Camptothecins

 

Peso molecular

545.56

Fòrmula

C30H28FN3O6
No. CAS
SMILES

O=C(C12CC(C1)(C2)O)N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

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Pureza y Documentación
Referencias
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Exatecan-amide-bicyclo[1.1.1]pentan-1-ol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Exatecan-amide-bicyclo[1.1.1]pentan-1-ol2866299-06-9ADC PayloadTopoisomeraseADC Cytotoxintumor cellpayloaddrug conjugatesInhibitorinhibitorinhibit

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Nombre del producto:
Exatecan-amide-bicyclo[1.1.1]pentan-1-ol
Cat. No.:
HY-160597
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