2. Metabolic Enzyme/Protease
  3. Ser/Thr Protease
  4. Factor VII-IN-1

Factor VII-IN-1 (example 43) is a potent inhibitor of factor VII (FVII), with an IC50 of 1.1 μM. Factor VII-IN-1 shows anticoagulant properties.

For research use only. We do not sell to patients.

Factor VII-IN-1

Factor VII-IN-1 Chemical Structure

CAS No. : 244206-28-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 mg In-stock
5 mg In-stock
10 mg In-stock
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Based on 1 publication(s) in Google Scholar

Factor VII-IN-1 Related Antibodies

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Description

Factor VII-IN-1 (example 43) is a potent inhibitor of factor VII (FVII), with an IC50 of 1.1 μM. Factor VII-IN-1 shows anticoagulant properties[1].

IC50 & Target

IC50: 1.1 μM (Factor VII)[1]
Molecular Weight

332.15

Formula

C15H10BrNO3
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C1OC(C2=CC(OC)=CC=C2Br)=NC3=CC=CC=C13
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (150.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0107 mL 15.0534 mL 30.1069 mL
5 mM 0.6021 mL 3.0107 mL 6.0214 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0107 mL 15.0534 mL 30.1069 mL 75.2672 mL
5 mM 0.6021 mL 3.0107 mL 6.0214 mL 15.0534 mL
10 mM 0.3011 mL 1.5053 mL 3.0107 mL 7.5267 mL
15 mM 0.2007 mL 1.0036 mL 2.0071 mL 5.0178 mL
20 mM 0.1505 mL 0.7527 mL 1.5053 mL 3.7634 mL
25 mM 0.1204 mL 0.6021 mL 1.2043 mL 3.0107 mL
30 mM 0.1004 mL 0.5018 mL 1.0036 mL 2.5089 mL
40 mM 0.0753 mL 0.3763 mL 0.7527 mL 1.8817 mL
50 mM 0.0602 mL 0.3011 mL 0.6021 mL 1.5053 mL
60 mM 0.0502 mL 0.2509 mL 0.5018 mL 1.2545 mL
80 mM 0.0376 mL 0.1882 mL 0.3763 mL 0.9408 mL
100 mM 0.0301 mL 0.1505 mL 0.3011 mL 0.7527 mL
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Factor VII-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Factor VII-IN-1244206-28-8Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasestissue factorclottingblood clotting factoranticoagulantInhibitorinhibitorinhibit

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