Fenoldopam mesylate (Standard)

(Synonyms: Fenoldopam methanesulfonate (Standard); SKF-82526 mesylate (Standard))

Fenoldopam mesylate (Standard) is the analytical standard of Fenoldopam mesylate (HY-B0735A). This product is intended for research and analytical applications. Fenoldopam (SKF-82526) mesylate is a selective dopamine D1 receptor agonist. Fenoldopam mesylate binds to rat D1B dopamine receptors (Kd = 11 nM) and human D1A receptors (Kd = 17 nM) in COS-7 cell membranes expressing the cloned receptors. Fenoldopam mesylate modulates dopamine receptor expression, induces vasorelaxation in vascular tissues, reverses glomerular hyperfiltration in rat models, increases intracellular cAMP levels, promotes DARPP-32 phosphorylation in small cell lung cancer (SCLC) cells, inhibits cytokine secretion, and downregulates T cell activation markers in activated human T cells. Fenoldopam mesylate can be used for research on hypertension, acute kidney injury, psoriasis, and small cell lung cancer.

For research use only. We do not sell to patients.

  • Purity: 98%
  • CAS No.: 67227-57-0
  • Formula: C₁₇H₂₀ClNO₆S
  • Molecular Weight:401.86
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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