Ferroptosis-IN-10
Ferroptosis-IN-10 (compound D1) is an inhibitor of ferroptosis with an IC50 value of 22 nM. Ferroptosis-IN-10 has neuroprotection activity in an oxygen-glucose deprivation/reoxygenation (OGD/R) model.
For research use only. We do not sell to patients.
- CAS No.: 3076686-62-6
- Formula: C14H20N6
- Molecular Weight:272.35
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HT-1080 | IC50 |
22 nM
Compound: D1
|
Anti-ferroptotic activity against Erastin-induced human HT-1080 cells assessed as inhibition of ferroptosis incubated for 72 hrs by CCK-8 assay
Anti-ferroptotic activity against Erastin-induced human HT-1080 cells assessed as inhibition of ferroptosis incubated for 72 hrs by CCK-8 assay
|
[PMID: 38996382] |
Chemical Information
-
CAS No. 3076686-62-6
-
Molecular Weight 272.35
-
Formula C14H20N6
-
SMILES
NC1=CC=C(C=C1NC2CCCCC2)C3=NN(N=N3)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)