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Cat. No.: HY-149719

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Ferroptosis-IN-4

Ferroptosis-IN-4 (compound 6k) is a ferroptosis inhibitor with EC₅₀ value of 20 μM. Ferroptosis-IN-4 has no obvious cytotoxicity. Ferroptosis-IN-4 has a protective effect in glycerol-induced RM-AKI mice with alleviating kidney dysfunction.

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CAS No.: 2798922-35-5
화학식: C₁₇H₂₄ClN₃O₂
분자량:337.84

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Ferroptosis-IN-4 Chemical Structure

CAS No.: 2798922-35-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
HK-2	CC₅₀	>100 μM Compound: 6k	Cytotoxicity against human HK-2 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Cytotoxicity against human HK-2 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 37976703]
HK-2	EC₅₀	20 μM Compound: 6k	Inhibition of RSL-3 induced ferroptosis in human HK-2 cells incubated for 48 hrs in presence of FAC Inhibition of RSL-3 induced ferroptosis in human HK-2 cells incubated for 48 hrs in presence of FAC	[PMID: 37976703]

Chemical Information

CAS No. 2798922-35-5
분자량 337.84
화학식 C₁₇H₂₄ClN₃O₂
SMILES

CN(CCN(C)C)C1=CC=C(N2C(C)=C(O)C(C=C2)=O)C=C1.Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jie Cen, et al. Synthesis and structure-activity optimization of hydroxypyridinones against rhabdomyolysis-induced acute kidney injury. Eur J Med Chem. 2023. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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