Flusulfinam
Flusulfinam is a HPPD inhibitor and herbicide, with an IC50 of 0.0181 μM against Arabidopsis thaliana HPPD. Flusulfinam inhibits the catalytic activity of recombinant Arabidopsis thaliana HPPD. Flusulfinam exhibits potent herbicidal activity against barnyard grass (Echinochloa crus-galli). Flusulfinam inhibits the growth of Digitaria sanguinalis.
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- CAS. Nr.: 2428458-82-4
- Formel: C14H13F4N3O3S
- Molecular Weight:379.33
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Biologische Aktivität
Beschreibung
In Vitro
Flusulfinam (0.94-30 g a.i. ha-1) exhibits strong herbicidal activity against barnyardgrass (Echinochloa crus-galli), inducing leaf chlorosis and plant death, with a GR50 value of 3.7235 ± 0.7995 g a.i. ha-1[1].
Flusulfinam (25 mg/L) reduces the chlorophyll content in Spirodela polyrhiza[1].
Flusulfinam potently inhibits the catalytic activity of recombinant Arabidopsis thaliana HPPD in vitro, with an IC50 of 0.0181 ± 0.0021 μM, which is 16 times more potent than Mesotrione[1].
Foliar application of Flusulfinam inhibits the growth of Digitaria sanguinalis, with an EC50 of 21.91 mg/L[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2428458-82-4
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Molecular Weight 379.33
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Formel C14H13F4N3O3S
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SMILES
O=C(NC1=NN=C(O1)C)C2=CC=C(C(=C2F)S(=O)CCC)C(F)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
[1]. Wang H, et al. Flusulfinam, a novel amide herbicide to control weed in rice fields, targets 4-hydroxyphenylpyruvate dioxygenase. Pestic Biochem Physiol. 2025;208:106240. [Content Brief]
[2]. Liu S, et al. Novel herbicide flusulfinam: absolute configuration, enantioseparation, enantioselective bioactivity, toxicity and degradation in paddy soils. Pest Manag Sci. 2024;80(10):5244-5255. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Flusulfinam Related Classifications
HY-W1115537 Related Classifications
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