Flusulfinam 

Flusulfinam is a HPPD inhibitor and herbicide, with an IC₅₀ of 0.0181 μM against Arabidopsis thaliana HPPD. Flusulfinam inhibits the catalytic activity of recombinant Arabidopsis thaliana HPPD. Flusulfinam exhibits potent herbicidal activity against barnyard grass (Echinochloa crus-galli). Flusulfinam inhibits the growth of Digitaria sanguinalis^[1][2].

Flusulfinam (0.94-30 g a.i. ha^-1) exhibits strong herbicidal activity against barnyardgrass (Echinochloa crus-galli), inducing leaf chlorosis and plant death, with a GR₅₀ value of 3.7235 ± 0.7995 g a.i. ha^-1[1].
Flusulfinam (25 mg/L) reduces the chlorophyll content in Spirodela polyrhiza^[1].
Flusulfinam potently inhibits the catalytic activity of recombinant Arabidopsis thaliana HPPD in vitro, with an IC₅₀ of 0.0181 ± 0.0021 μM, which is 16 times more potent than Mesotrione^[1].
Foliar application of Flusulfinam inhibits the growth of Digitaria sanguinalis, with an EC₅₀ of 21.91 mg/L^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Flusulfinam (exposure; 96 h) exhibits acute toxicity to zebrafish (Danio rerio) larvae, with an LC₅₀ of 62.61 mg/L^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

379.33

C₁₄H₁₃F₄N₃O₃S

2428458-82-4

O=C(NC1=NN=C(O1)C)C2=CC=C(C(=C2F)S(=O)CCC)C(F)(F)F

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Wang H, et al. Flusulfinam, a novel amide herbicide to control weed in rice fields, targets 4-hydroxyphenylpyruvate dioxygenase. Pestic Biochem Physiol. 2025;208:106240.  [Content Brief]

  [2]. Liu S, et al. Novel herbicide flusulfinam: absolute configuration, enantioseparation, enantioselective bioactivity, toxicity and degradation in paddy soils. Pest Manag Sci. 2024;80(10):5244-5255.  [Content Brief]