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Cat. No.: HY-163281

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FSY-OSO2F

Name: FSY-OSO2F
Brand: MedChemExpress
SKU: HY-163281
Availability: PreOrder

FSY-OSO2F is (S)-2-amino-3-(4-((fluorosulfonyl) oxy) phenyl) propanoic acid. The radiolabeled form of FSY-OSO2F, ([¹⁸F]FSY-OSO2F), serves as a PET tracer that is taken up by cancer cells. FSY-OSO2F can be used in research related to cancer and PET imaging.

For research use only. We do not sell to patients.

CAS No.: 1839622-49-9
Formula: C₉H₁₀FNO₅S
Molecular Weight:263.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

FSY-OSO2F Chemical Structure

CAS No.: 1839622-49-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
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Biological Activity

Description

In Vitro

FSY-OSO2F radiolabeled with ¹⁸F exhibits time-dependent cellular accumulation in MCF-7 cells. Competitive inhibition assays verify that the resulting [¹⁸F]FSY-OSO2F internalizes via specific amino acid transport systems and retains over 95% radiochemical purity after 120 min of plasma incubation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

In Vivo

FSY-OSO2F radiolabeled with ¹⁸F ([¹⁸F]FSY-OSO2F) (8–11 MBq; single intravenous administration) is utilized for small-animal dynamic PET-CT imaging and static PET blocking experiments in female nude mice bearing MCF-7 breast cancer xenografts, 22Rv1 prostate cancer xenografts, and intracranial U87MG glioblastoma xenografts; normalized time–activity curves can be acquired from tumor regions of interest during dynamic imaging^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1839622-49-9
Molecular Weight 263.24
Formula C₉H₁₀FNO₅S
SMILES

O=C(O)[C@@H](N)CC1=CC=C(OS(=O)(F)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Huang Y, et al. Design of Novel 18F-Labeled Amino Acid Tracers Using Sulfur 18F-Fluoride Exchange Click Chemistry. ACS Med Chem Lett. 2024 Jan 25;15(2):294-301. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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