G-418 disulfate (Standard)
Based on 1 Customer Validation
G-418 (disulfate) (Standard) is the analytical standard of G-418 (disulfate). This product is intended for research and analytical applications. G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells[1].
For research use only. We do not sell to patients.
- Purity: 95.22%
- CAS No.: 108321-42-2
- Formula: C20H44N4O18S2
- Molecular Weight:692.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 108321-42-2
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Appearance Solid
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Molecular Weight 692.71
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Formula C20H44N4O18S2
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Color White to off-white
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SMILES
O=S(O)(O)=O.O[C@@H]([C@@H]1O[C@@]([C@@H]([C@@H](O)[C@@H]2O)N)([H])O[C@]2([H])[C@H](O)C)[C@H]([C@@H](C[C@@H]1N)N)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O.O=S(O)(O)=O
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Synonyms
Geneticin sulfate (Standard); Antibiotic G-418 sulfate (Standard)
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Giordano-Santini R, et al. An antibiotic selection marker for nematode transgenesis. Nat Methods. 2010;7(9):721-723. [Content Brief]
[2]. Volarevic M, et al. A novel G418 conjugate results in targeted selection of genetically protected hepatocytes without bystander toxicity. Bioconjug Chem. 2007;18(6):1965-1971. [Content Brief]
[3]. Kwon KM, et al. Disialyl GD2 ganglioside suppresses ICAM-1-mediated invasiveness in human breast cancer MDA-MB231 cells. Int J Biol Sci. 2017;13(3):265-275. Published 2017 Feb 12. [Content Brief]
[4]. Davies J, et al. A new selective agent for eukaryotic cloning vectors. Am J Trop Med Hyg. 1980;29(5 Suppl):1089-1092. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)