GABAA receptor agent 6
GABAA receptor agent 6 (compound 2027) is a potent γ-GABAAR antagonist with an Ki of 0.56 µM. GABAA receptor agent 6 shows γ-GABAAR antagonist activity with low cellular membrane permeability.
For research use only. We do not sell to patients.
- CAS No.: 1808463-81-1
- Formula: C18H25N3O2
- Molecular Weight:315.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Ki: 0.56 µM (γ-GABAAR)[1]
GABAA receptor agent 6 (compound 2027) shows antagonist activity with IC50s of 6.68, 1.03, 0.36, 4.13, 4.96, 2.96, 0.29, 0.59 µM for α1β2δ, α4β1δ, α4β2δ, α6β2δ, α1β2γ2, α2β2γ2, α3β2γ2, α5β2γ2 subtypes, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1808463-81-1
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Molecular Weight 315.41
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Formula C18H25N3O2
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SMILES
O=C(C)NC1=CC=CC(C(N2CCC3(CC2)CCNCC3)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GABAA receptor agent 6 Related Classifications
HY-145258 Related Classifications
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- GABAA receptor agent 6
- 1808463-81-1
- GABAA receptor agent6
- GABAA receptor agent-6
- GABA Receptor
- GABAA receptor agent 6 (compound 2027) shows antagonist activity with IC50s of 6.68
- 1.03
- 0.36
- 4.13
- 4.96
- 2.96
- 0.29
- 0.59 μM for α1β2δ
- α4β1δ
- α4β2δ
- α6β2δ
- α1β2γ2
- α2β2γ2
- α3β2γ2
- α5β2γ2 subtypes
- respectively[1].
- Inhibitor
- inhibitor
- inhibit