GABAA receptor modulator-5
GABAA receptor modulator-5 (Compound S28) is a modulator for (γ-aminobutyric acid)A receptor (GABAA receptor), with EC50 of 56 nM and 10 nM, for α1β2γ2 and α4β3δ subtype. GABAA receptor modulator-5 exhibits good pharmacokinetic characteristics in rats. GABAA receptor modulator-5 is slightly toxic toxicity in rats with a loss of rollover reflex (LORR) threshold dose of 23.3 μmol/kg, and exhibits potential ameliorating the postpartum depression.
For research use only. We do not sell to patients.
- CAS No.: 3021554-08-2
- Formula: C28H36F2N4O3
- Molecular Weight:514.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 56 nM (GABAA receptor α1β2γ2); 10 nM (GABAA receptor α4β3δ)
Chemical Information
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CAS No. 3021554-08-2
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Molecular Weight 514.61
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Formula C28H36F2N4O3
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SMILES
C[C@@]12[C@](CC[C@@H]2C(CN3C=NN(C4=CC(F)=NC(F)=C4)C3=O)=O)([H])[C@]5([H])CC[C@]6([H])C[C@@](O)(C)CC[C@]6([H])[C@@]5([H])CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GABAA receptor modulator-5 Related Classifications
HY-161784 Related Classifications
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