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Cat. No.: HY-107775R

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Ganfeborole hydrochloride (Standard)

Name: Ganfeborole hydrochloride (Standard)
Brand: MedChemExpress
SKU: HY-107775R
Price: 440.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: GSK656 (Standard); GSK3036656 (Standard); GSK070 (Standard))

Ganfeborole hydrochloride (Standard) is the analytical standard of Ganfeborole (hydrochloride) (HY-107775). This product is intended for research and analytical applications. Ganfeborole hydrochloride (GSK656) is a potent antitubercular agent, acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC₅₀ of 0.2 μM.

For research use only. We do not sell to patients.

Purity: 98%
CAS No.: 2131798-13-3
Formula: C₁₀H₁₄BCl₂NO₄
Molecular Weight:293.94

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ganfeborole hydrochloride (Standard) Chemical Structure

CAS No.: 2131798-13-3

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HY-107775

Ganfeborole hydrochloride

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 2131798-13-3
Molecular Weight 293.94
Formula C₁₀H₁₄BCl₂NO₄
SMILES

OB1O[C@H](CN)C2=C(Cl)C=CC(OCCO)=C21.[H]Cl
Synonyms

GSK656 (Standard); GSK3036656 (Standard); GSK070 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Li X, et al. Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656). J Med Chem. 2017 Oct 12;60(19):8011-8026. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Ganfeborole hydrochloride (Standard)

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Ganfeborole hydrochloride (Standard)