2-Chlorophenothiazine
Based on 1 Customer Validation
2-Chlorophenothiazine is a phenothiazine derivative. 2-Chlorophenothiazine has the activity of inhibiting DNA, RNA and protein synthesis. 2-Chlorophenothiazine is an intermediate in the synthesis of Chlorpromazine (HY-12708) and Perphenazine (HY-A0077).
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- No. CAS: 92-39-7
- Fòrmula: C12H8ClNS
- Peso molecular:233.72
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Almacenamiento:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-Y1749R
2-Chlorophenothiazine (Standard)Drug Intermediate -
HY-W012258
2-MethoxyphenothiazineBiochemical Assay Reagent -
HY-W011996
2-Methylthiophenothiazine -
HY-W012258R
2-Methoxyphenothiazine (Standard)Biochemical Assay Reagent -
HY-W008601
Trazodone impurity 5 hydrochlorideDrug Impurity -
HY-W010593
EthylenethioureaTumorigenic Agent -
HY-W015626
2,5-DichloropyridineBiochemical Reagent -
HY-W008601R
Trazodone impurity 5 hydrochloride (Standard) -
HY-W010593R
Ethylenethiourea (Standard)Tumorigenic Agent
Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| K562 | IC50 |
>100 μM
Compound: 14
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Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis
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[PMID: 21563750] |
Chemical Information
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No. CAS 92-39-7
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Appearance Solid
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Peso molecular 233.72
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Fòrmula C12H8ClNS
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SMILES
ClC(C=C1N2)=CC=C1SC3=C2C=CC=C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvente y solubilidad
In Vitro:
DMSO : 25 mg/mL (106.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2786 mL | 21.3931 mL | 42.7862 mL | 106.9656 mL |
| 5 mM | 0.8557 mL | 4.2786 mL | 8.5572 mL | 21.3931 mL | |
| 10 mM | 0.4279 mL | 2.1393 mL | 4.2786 mL | 10.6966 mL | |
| 15 mM | 0.2852 mL | 1.4262 mL | 2.8524 mL | 7.1310 mL | |
| 20 mM | 0.2139 mL | 1.0697 mL | 2.1393 mL | 5.3483 mL | |
| 25 mM | 0.1711 mL | 0.8557 mL | 1.7114 mL | 4.2786 mL | |
| 30 mM | 0.1426 mL | 0.7131 mL | 1.4262 mL | 3.5655 mL | |
| 40 mM | 0.1070 mL | 0.5348 mL | 1.0697 mL | 2.6741 mL | |
| 50 mM | 0.0856 mL | 0.4279 mL | 0.8557 mL | 2.1393 mL | |
| 60 mM | 0.0713 mL | 0.3566 mL | 0.7131 mL | 1.7828 mL | |
| 80 mM | 0.0535 mL | 0.2674 mL | 0.5348 mL | 1.3371 mL | |
| 100 mM | 0.0428 mL | 0.2139 mL | 0.4279 mL | 1.0697 mL |
2-Chlorophenothiazine Related Classifications
HY-Y1749 Related Classifications
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