E-6123
E-6123 is a platelet-activating factor (PAF) receptor antagonist.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 131614-02-3
- Fòrmula: C23H22ClN5OS
- Peso molecular:451.97
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
PAF[1]
In Vitro
E-6123 (E6123) partially inhibits the Thapsigargin-induced increase in the levels of interleukin-6 mRNA and interleukin-6 protein. To clarify the role of the concurrently produced cell-associated PAF in the thapsigargin-induced increase in the interleukin-6 mRNA level and interleukin-6 production, the effects of the PAF receptor antagonist E-6123 are examined. E-6123 at 1 and 10 μM partially inhibits the Thapsigargin (46.1 nM)-induced increase in the interleukin-6 mRNA level at 4 h and interleukin-6 production at 8 h[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 131614-02-3
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Peso molecular 451.97
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Fòrmula C23H22ClN5OS
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SMILES
O=C(C1CC1)N2CC3=C(CC2)C(C(C4=CC=CC=C4Cl)=N[C@H]5C)=C(S3)N6C5=NN=C6C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
E-6123 Related Classifications
HY-10164 Related Classifications
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