AMI-1 (Standard)
AMI-1 (Standard) is the analytical standard of AMI-1. This product is intended for research and analytical applications. AMI-1 is a potent, cell-permeable and reversible inhibitor of protein arginine N-methyltransferases (PRMTs), with IC50s of 8.8 μM and 3.0 μM for human PRMT1 and yeast-Hmt1p, respectively. AMI-1 exerts PRMTs inhibitory effects by blocking peptide-substrate binding.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 95%
- No. CAS: 20324-87-2
- Fòrmula: C21H14N2Na2O9S2
- Peso molecular:548.45
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Pureza y Documentación
-
Help & FAQs
-
HY-18962
AMI-1PRMTs Inhibitor -
HY-19715
SGC707PRMT3 Inhibitor -
HY-19615
MS023Type I PRMT Inhibitor -
HY-100235
GSK591PRMT5 Inhibitor -
HY-12970A
EPZ020411 hydrochloridePRMT6 Inhibitor -
HY-15593
PinometostatDOT1L Inhibitor -
HY-12727
EPZ015666PRMT5 Inhibitor -
HY-101563
PemrametostatPRMT5 Inhibitor -
HY-N2019
ChaetocinSU(VAR)3-9 Inhibitor -
HY-12970
EPZ020411PRMT6 Inhibitor -
HY-13803
TazemetostatEZH2 Inhibitor -
HY-13470
GSK126EZH2 Inhibitor
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
No. CAS 20324-87-2
-
Peso molecular 548.45
-
Fòrmula C21H14N2Na2O9S2
-
SMILES
O=C(NC1=CC2=CC(S(=O)(O[Na])=O)=CC(O)=C2C=C1)NC3=CC4=CC(S(=O)(O[Na])=O)=CC(O)=C4C=C3
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Zhang, B., et al. Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3. Oncotarget. 2015 Sep 8;6(26):22799-811. [Content Brief]
[2]. Baolai Zhang, et al. Arginine Methyltransferase inhibitor-1 Inhibits Sarcoma Viability in vitro and in vivo. Oncol Lett. 2018 Aug;16(2):2161-2166. [Content Brief]
[3]. Donghang Cheng, et al. Small Molecule Regulators of Protein Arginine Methyltransferases. J Biol Chem. 2004 Jun 4;279(23):23892-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AMI-1 (Standard) Related Classifications
HY-18962R Related Classifications
Powered by Bioz