F1-ispinesib
F1-ispinesib is a heterobifunctional F1-autophagy degrader, composed of an RNA-binding fragment (F1) and the LC3B ligand Ispinesib (HY-50759). F1-ispinesib induces degradation of COL15A1 mRNA via an LC3B-dependent macroautophagy mechanism. F1-ispinesib inhibits cell proliferation and enhances migration of human aortic smooth muscle cells.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C51H52Cl3N5O4
- Peso molecular:905.35
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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Peso molecular 905.35
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Fòrmula C51H52Cl3N5O4
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SMILES
CC1=CC=C(C=C1)C(N([C@H](C(C)C)C2=NC3=C(C(N2CC4=CC=CC=C4)=O)C=CC(Cl)=C3)CCCNC(CCC(N([C@H]5CC[C@H](C6=C5C=CC=C6)C7=CC=C(C(Cl)=C7)Cl)C)=O)=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
F1-ispinesib Related Classifications
HY-180188 Related Classifications
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