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Referencia número: HY-128037

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FTase-IN-2

FTase-IN-2 (Compound 2) is a farnesyltransferase inhibitor, with IC₅₀ values of 150 nM and 1500 nM against FTase and GGTase I, respectively. FTase-IN-2 is not farnesylated by FTase, thus avoiding metabolic inactivation.

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No. CAS: 156707-43-6
Fòrmula: C₁₅H₂₁N₃O₄S₂
Peso molecular:371.47

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

FTase-IN-2 Chemical Structure

No. CAS: 156707-43-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Chemical Information

No. CAS 156707-43-6
Peso molecular 371.47
Fòrmula C₁₅H₂₁N₃O₄S₂
SMILES

N(C([C@H](CS)N)=O)C1=CC=C(C(N[C@@H](CCSC)C(O)=O)=O)C=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocolo

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Vogt A, et al. A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processing. The Journal of biological chemistry. 1995 Jan 13;270(2):660-4. [Content Brief]

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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