Herbimycin C
Herbimycin C is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells (IC50s=7.3 and 1.2 μg/mL, respectively).
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- No. CAS: 91700-92-4
- Fòrmula: C29H40N2O9
- Peso molecular:560.64
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
3.01 μM
Compound: 2
|
Antiproliferative activity against human A2780 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human A2780 assessed as reduction in cell viability measured after 96 hrs by MTT assay
|
[PMID: 27476419] |
| A-375 | IC50 |
2.43 μM
Compound: 2
|
Antiproliferative activity against human A375 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human A375 assessed as reduction in cell viability measured after 96 hrs by MTT assay
|
[PMID: 27476419] |
| BGC-823 | IC50 |
3.99 μM
Compound: 2
|
Antiproliferative activity against human BGC823 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human BGC823 assessed as reduction in cell viability measured after 96 hrs by MTT assay
|
[PMID: 27476419] |
| HCT-116 | IC50 |
9.39 μM
Compound: 2
|
Antiproliferative activity against human HCT116 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human HCT116 assessed as reduction in cell viability measured after 96 hrs by MTT assay
|
[PMID: 27476419] |
| MCF7 | IC50 |
5.07 μM
Compound: 2
|
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human MCF7 assessed as reduction in cell viability measured after 96 hrs by MTT assay
|
[PMID: 27476419] |
| SW1990 | IC50 |
8.62 μM
Compound: 2
|
Antiproliferative activity against human SW1990 assessed as reduction in cell viability measured after 96 hrs by MTT assay
Antiproliferative activity against human SW1990 assessed as reduction in cell viability measured after 96 hrs by MTT assay
|
[PMID: 27476419] |
Chemical Information
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No. CAS 91700-92-4
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Peso molecular 560.64
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Fòrmula C29H40N2O9
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SMILES
CO[C@@]1([H])C(C(C(NC(/C(C)=C/C=C/[C@H](OC)[C@@H](OC(N)=O)/C(C)=C/[C@H](C)[C@@H](O)[C@@H](OC)C[C@@H]1C)=O)=C2)=O)=CC2=O
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Synonyms
Antibiotic TAN 420D
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)