Human UGT2B15
Based on 1 Customer Validation
Human UGT2B15 is a UDP-glucuronosyltransferase. Human UGT2B15 stereoselectively catalyzes the glucuronidation of S-Oxazepam. Human UGT2B15 does not mediate the glucuronidation of R-Oxazepam.
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
UGT2B15 |
In Vitro
Human UGT2B15 catalyzes the glucuronidation of S-Oxazepam, with an apparent Km value of 35 µM, and its kinetics conform to a non-competitive substrate inhibition model[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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SMILES
[Human UGT2B15]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Court MH, et al. Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9. Drug metabolism and disposition: the biological fate of chemicals. 2002 Nov;30(11):1257-65. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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