IAN-15B
IAN-15B has high selectivity and potent ST6GAL1 inhibitors (IC50 = 3.3 μM). IAN-15B has significant anti migratory and anti angiogenic effects. IAN-15B can be used in the research of cancer such as breast cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C44H55N9O4
- Peso molecular:773.97
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Chemical Information
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Peso molecular 773.97
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Fòrmula C44H55N9O4
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SMILES
[H][C@]12CC[C@@]3([C@H](CC[C@]3([C@@]1(CC[C@@]4(C[C@@H](CC[C@]24C)O)[H])[H])[H])[C@@H](CCC(N[C@@H](C(O)=O)CC(C5=CNC6=C5C=C(C=C6)N=[N+]=[N-])C7=CNC8=C7C=C(C=C8)N=[N+]=[N-])=O)C)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)