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United States

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Referencia número: HY-123608

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JE-2178

JE-2178 is an orally available HIV-1 protease inhibitor with IC₅₀ and K_i values are 15 and 0.318 nM respectively. JE-2178 has antiviral activity.

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No. CAS: 210181-19-4
Fòrmula: C₃₅H₅₁N₅O₆S
Peso molecular:669.87

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

JE-2178 Chemical Structure

No. CAS: 210181-19-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

JE-2178 is an orally available HIV-1 protease inhibitor with IC₅₀ and K_i values are 15 and 0.318 nM respectively. JE-2178 has antiviral activity^[1].

Chemical Information

No. CAS 210181-19-4
Peso molecular 669.87
Fòrmula C₃₅H₅₁N₅O₆S
SMILES

O[C@@H]([C@H](CC1=CC=CC=C1)NC([C@H](C(C)C)NC(COC2=CC=CC(N(C)C)=C2)=O)=O)C(N3CSC(C)([C@H]3C(NC(C)(C)C)=O)C)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Mimoto T, et al. Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere. Chem Pharm Bull (Tokyo). 2000 Sep;48(9):1310-26. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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