KSK213
KSK213 is a 1,2,3-triazole-based Chlamydia infectivity inhibitor with high potency (EC50 ≤ 20 nM) against Chlamydia infectivity.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1876429-73-0
- Fòrmula: C28H25N3O2S
- Peso molecular:467.58
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | EC50 |
58 nM
Compound: 21a
|
Antimicrobial activity against Chlamydia trachomatis serovar D infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay
Antimicrobial activity against Chlamydia trachomatis serovar D infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay
|
[PMID: 26849778] |
| HeLa | EC50 |
59 nM
Compound: 21a
|
Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay
Antimicrobial activity against Chlamydia trachomatis serovar LGV-L2 infected in human HeLa cells assessed as decrease in relative inclusion forming units measured 44 to 48 hrs post infection by DAPI staining-based assay
|
[PMID: 26849778] |
Chemical Information
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No. CAS 1876429-73-0
-
Peso molecular 467.58
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Fòrmula C28H25N3O2S
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SMILES
O=C(C1CSC2=C(C3CC3)C(CC4=C5C=CC=CC5=CC=C4)=C(N)C(N21)=O)NC6=CC=CC=C6
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)