MK-1832
MK-1832 (Compound 32) is a selective Kv1.5 inhibitor (IC50 = 86 nM). MK-1832 is a P-glycoprotein substrate. MK-1832 can be used in atrial fibrillation research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 935868-50-1
- Fòrmula: C23H17Cl2N3O
- Peso molecular:422.31
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
>30000 nM
Compound: 2; MK-1832; ent-32
|
Displacement of [3H]-MK499 from human ERG IKr channel expressed in HEK293 cell membranes
Displacement of [3H]-MK499 from human ERG IKr channel expressed in HEK293 cell membranes
|
[PMID: 28131713] |
Chemical Information
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No. CAS 935868-50-1
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Peso molecular 422.31
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Fòrmula C23H17Cl2N3O
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SMILES
O[C@@H](C1=CC=CN=C1C2=CC(Cl)=CC(Cl)=C2)C(C3=CC=CN=C3)C4=CC=CN=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)