Nemazoline
Nemazoline (A-57219) is selective α-adrenergic agent with α1-agonist/α2-antagonist activity, which is used as a nasal decongestant. Nemazoline produces decongestion by α1-mediated contraction of capacitance vessels, but not compromises blood flow by virtue of α2-antagonism. Nemazoline also blocks endogenous noradrenaline-mediated α 2-constriction of the resistance vessels.
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- No. CAS: 130759-56-7
- Fòrmula: C10H11Cl2N3
- Peso molecular:244.12
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
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α1-adrenergic receptor |
α2-adrenergic receptor |
Chemical Information
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No. CAS 130759-56-7
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Peso molecular 244.12
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Fòrmula C10H11Cl2N3
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SMILES
NC1=C(C=C(C=C1Cl)CC2=NCCN2)Cl
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Synonyms
A-57219 free base; SCH 40054 free base
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nemazoline Related Classifications
HY-W650803 Related Classifications
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