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Cat. No.: HY-106798

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Nemazoline hydrochloride

Name: Nemazoline hydrochloride
Brand: MedChemExpress
SKU: HY-106798
Availability: PreOrder

(Synonyms: A-57219; SCH 40054)

Nemazoline hydrochloride (A-57219 hydrochloride) is selective α-adrenergic agent with α₁-agonist/α₂-antagonist activity, which is used as a nasal decongestant. Nemazoline hydrochloride produces decongestion by α₁-mediated contraction of capacitance vessels, but not compromises blood flow by virtue of α₂-antagonism. Nemazoline hydrochloride also blocks endogenous noradrenaline-mediated α ₂-constriction of the resistance vessels.

For research use only. We do not sell to patients.

CAS No.: 111073-18-8
Formula: C₁₀H₁₂Cl₃N₃
Molecular Weight:280.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Nemazoline hydrochloride Chemical Structure

CAS No.: 111073-18-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 111073-18-8
Molecular Weight 280.58
Formula C₁₀H₁₂Cl₃N₃
SMILES

ClC1=C(N)C(Cl)=CC(CC2=NCCN2)=C1.Cl
Synonyms

A-57219; SCH 40054
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. DeBernardis JF, et al. A new nasal decongestant, A-57219: a comparison with oxymetazoline. J Pharm Pharmacol. 1987 Sep;39(9):760-3. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Nemazoline hydrochloride

All Adrenergic Receptor Isoforms