Boc-NH-PEG3
Based on 1 Customer Validation
Boc-NH-PEG3 (PROTAC Linker 10) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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- Pureza: 98.0%
- No. CAS: 139115-92-7
- Fòrmula: C11H23NO5
- Peso molecular:249.30
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Almacenamiento:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 139115-92-7
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Appearance Liquid (Density: 1.071±0.06 g/cm3)
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Peso molecular 249.30
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Fòrmula C11H23NO5
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)NCCOCCOCCO
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Synonyms
PROTAC Linker 10
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 100 mg/mL (401.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0112 mL | 20.0562 mL | 40.1123 mL | 100.2808 mL |
| 5 mM | 0.8022 mL | 4.0112 mL | 8.0225 mL | 20.0562 mL | |
| 10 mM | 0.4011 mL | 2.0056 mL | 4.0112 mL | 10.0281 mL | |
| 15 mM | 0.2674 mL | 1.3371 mL | 2.6742 mL | 6.6854 mL | |
| 20 mM | 0.2006 mL | 1.0028 mL | 2.0056 mL | 5.0140 mL | |
| 25 mM | 0.1604 mL | 0.8022 mL | 1.6045 mL | 4.0112 mL | |
| 30 mM | 0.1337 mL | 0.6685 mL | 1.3371 mL | 3.3427 mL | |
| 40 mM | 0.1003 mL | 0.5014 mL | 1.0028 mL | 2.5070 mL | |
| 50 mM | 0.0802 mL | 0.4011 mL | 0.8022 mL | 2.0056 mL | |
| 60 mM | 0.0669 mL | 0.3343 mL | 0.6685 mL | 1.6713 mL | |
| 80 mM | 0.0501 mL | 0.2507 mL | 0.5014 mL | 1.2535 mL | |
| 100 mM | 0.0401 mL | 0.2006 mL | 0.4011 mL | 1.0028 mL |