S07-2001
S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer agent resistance.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1197904-57-6
- Fòrmula: C15H17N3O4S
- Peso molecular:335.38
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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- Pureza y Documentación
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
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AKR1C3 2.08 μM (IC50) |
In Vitro
S07-2001 (50 μM) reduces 27% of MCF-7 cell viability administrated with Doxorubicin[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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No. CAS 1197904-57-6
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Peso molecular 335.38
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Fòrmula C15H17N3O4S
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SMILES
O=C(C1=CC(C(C)=O)=CN1)NCC2=CC=C(CS(=O)(N)=O)C=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
S07-2001 Related Classifications
HY-150650 Related Classifications
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