sAJM589
Based on 2 publication(s) in Google Scholar
sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM.
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- Pureza: 99.47%
- No. CAS: 2089-82-9
- Fòrmula: C16H10N2O
- Peso molecular:246.26
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) sAJM589
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Actividad biológica
IC50: 1.8 μM (Myc)[1]
sAJM589 potently disrupts the Myc-Max heterodimer to reduce Myc protein levels in a dose dependent manner, with an IC50 of 1.8 μM[1].
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sAJM589 suppresses cellular proliferation in diverse Myc-dependent cancer cell lines and anchorage independent growth of Raji cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2089-82-9
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Appearance Solid
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Peso molecular 246.26
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Fòrmula C16H10N2O
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Color Yellow to orange
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SMILES
OC1=CC2=NC3=CC=CC=C3N=C2C4=CC=CC=C41
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Biochim Biophys Acta Gen Subj
5-Hydroxytryptamine activates a 5-HT/c-Myc/SLC6A4 signaling loop in non-small cell lung cancer. [Abstract]2022 Apr;1866(4):130093. PMID: 35066124
Pureza y Documentación
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Ficha de datos (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)