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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10075 Results for "
function-oriented synthesis
" in MedChemExpress (MCE) Product Catalog:
Products (10075)
10075 Results for "function-oriented synthesis" in MCE Product Catalog:
450
Target:
450
450 Publications Verification
Synonyms: CL13900 dihydrochloride
Category:
Infection Microorganisms Antibiotics Resistance Selection Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
356
301
301 Cited Publications
Referencia número: HY-B0003
No. CAS: 122111-03-9
Synonyms: LY 188011 hydrochloride
Áreas de investigación:
Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis .
237
237 Cited Publications
Referencia número: HY-17371
No. CAS: 61825-94-3
Target:
Áreas de investigación:
Oxaliplatin is a DNA synthesis inhibitor. Oxaliplatin causes DNA crosslinking damage, prevents DNA replication and transcription and induces apoptosis. Oxaliplatin can be used for cancer research .
234
234 Cited Publications
Synonyms: MLN4924 hydrochloride
Target:
Áreas de investigación:
Pevonedistat (MLN4924) hydrochloride is a potent and selective NEDD8-activating enzyme (NAE) inhibitor, with an IC50 of 4.7 nM. Pevonedistat hydrochloride induces the deregulation of S-phase DNA synthesis, thereby disrupting protein turnover mediated by cullin-RING ligase, leading to apoptosis of human tumor cells. Pevonedistat hydrochloride suppresses the growth of human tumour xenografts in mice .
230
230 Cited Publications
Synonyms: GS-5734
Target:
Áreas de investigación:
Remdesivir (GS-5734) is a nucleoside analogue with effective antiviral activity. Remdesivir can inhibit the synthesis of viral DNA or RNA. Remdesivir can be used for the research of infection, such as SARS-CoV and MHV infection .
218
218 Cited Publications
Referencia número: HY-17565A
No. CAS: 67763-87-5
Target:
Áreas de investigación:
Bleomycin hydrochloride is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin hydrochloride is an antitumor antibiotic .
218
Category:
Microorganisms Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Anticancer Disease Research Fields Other Antibiotics Cancer
Target:
168
168 Cited Publications
Synonyms: Adenosine 5'-triphosphate disodium salt, 100 mM Solution, PCR Grade
163
163 Cited Publications
Referencia número: HY-18982
No. CAS: 22862-76-6
Synonyms: Flagecidin; Wuningmeisu C
120
120 Cited Publications
Referencia número: HY-B0069
No. CAS: 21679-14-1
Synonyms: F-ara-A; NSC 118218
Áreas de investigación:
Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes .
108
Category:
Disease Research Antibacterial Other Antibiotics Microorganisms Plant Cell Culture Antibiotics Phenols Polyphenols Disease Research Fields Cancer
Target:
106
106 Cited Publications
Synonyms: Cytosine β-D-arabinofuranoside hydrochloride; Cytosine Arabinoside hydrochloride; Ara-C hydrochloride
Cytarabine hydrochloride, a nucleoside analog, causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC50 of 16 nM. Cytarabine hydrochloride has antiviral effects against HSV.
106
106 Cited Publications
Synonyms: Cytosine β-D-arabinofuranoside; Cytosine Arabinoside; Ara-C
99
Áreas de investigación:
Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.
79
79 Cited Publications
Synonyms: 7-Ethyl-10-hydroxycamptothecin
78
78 Cited Publications
Referencia número: HY-K1057
Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes, causing premature chain termination during translation. It can kill most gram-positive bacteria and various animal or insect cells.
71
71 Cited Publications
Referencia número: HY-108718
No. CAS: 49863-47-0
Synonyms: Geneticin; Antibiotic G-418
Target:
Áreas de investigación:
G-418 (Geneticin) is an aminoglycoside antibiotic with a structure similar to gentamicin. It is toxic to both eukaryotic and prokaryotic cells and works by interfering with protein synthesis .
71
71 Cited Publications
Referencia número: HY-17561
No. CAS: 108321-42-2
Synonyms: Geneticin sulfate; Antibiotic G-418 sulfate
Category:
Antifungal Disease Research Antibacterial Other Antibiotics Infection Microorganisms Plant Cell Culture Antibiotics Resistance Selection Disease Research Fields
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
