SIK2/3-IN-2
SIK2/3-IN-2 (compound 12, compound I-200) is a potent SIK2/3 inhibitor (SIK2 IC50 = 65 nM, SIK3 IC50 = 14 nM). SIK2/3-IN-2 is also a p21-activated protein kinase (PAK) 1 inhibitor with a Ki of 20.7 nM. SIK2/3-IN-2 can be used for hyperproliferative diseases and cancer research, such as Paclitaxel (HY-B0015)-resistant ovarian cancer.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1648864-21-4
- Fòrmula: C25H25ClN6O3
- Peso molecular:492.96
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Descripciòn
|
PAK1 20.7 nM (Ki) |
QIK/SIK2 65 nM (IC50) |
QSK/SIK3 14 nM (IC50) |
Chemical Information
-
No. CAS 1648864-21-4
-
Peso molecular 492.96
-
Fòrmula C25H25ClN6O3
-
SMILES
O=C(N(C1=N2)C[C@H]3OC[C@@H](CO3)N)C(C4=C(C=C(C5=C(C=CC=N5)C)C=C4)Cl)=CC1=CN=C2NC
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SIK2/3-IN-2 Related Classifications
HY-164534 Related Classifications
Powered by Bioz