ST-1892
ST-1892 (compound 14) is a highly potent FXR agonist (EC50=7.2 nM) that can be used to study diseases or disorders caused by metabolic inflammation.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1409411-32-0
- Fòrmula: C16H12N2O3
- Peso molecular:280.28
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | EC50 |
0.0072 μM
Compound: 14
|
Agonist activity at human full length FXR expressed in HeLa cells cotransfected with pSG5-human RXR after 24 hrs by Dual-Glo luciferase reporter gene assay
Agonist activity at human full length FXR expressed in HeLa cells cotransfected with pSG5-human RXR after 24 hrs by Dual-Glo luciferase reporter gene assay
|
[PMID: 25934227] |
Chemical Information
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No. CAS 1409411-32-0
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Peso molecular 280.28
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Fòrmula C16H12N2O3
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SMILES
O=C(C1=CC=CC(C2=NC(C3=CC=CC=C3C)=NO2)=C1)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)