TLP-3
TLP-3, Temporin L (HY-P2523) analogue, is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 7.0 μM. TLP-3 inhibits protease activity through stabilizing hydrogen bonding and hydrophobic interactions with key enzyme residues. TLP-3 can be used for the research of ARS-CoV‑2 infection.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C83H110N20O17
- Peso molecular:1659.89
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
TLP-3 stabilizes SARS-CoV-2 Mpro via favorable domain arrangement and forms strong hydrogen bond interactions with critical Mpro residues[1].
TLP-3 inhibits SARS-CoV-2 Mpro with an IC50 of 7.0 ± 1.5 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Peso molecular 1659.89
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Fòrmula C83H110N20O17
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Sequence
Ser-Ala-Phe-Trp-Gln-Trp-Phe-Ser-Lys-Phe-Leu-Gly-Arg
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Sequence Shortening
SAFWQWFSKFLGR
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)