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Referencia número: HY-111281

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UK 39671

UK 39671 is a store-operated calcium permeability inhibitor with an IC₅₀ of 10 μM in thymocytes. UK 39671 prevents the acceleration of Mn²⁺ influx in thymocytes with intracellular calcium store depletion.

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No. CAS: 85473-17-2
Fòrmula: C₁₇H₂₂Cl₂N₂O
Peso molecular:341.28

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

UK 39671 Chemical Structure

No. CAS: 85473-17-2

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Actividad biológica
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Actividad biológica

Descripciòn

In Vitro

UK 39671 (10 μM) potently inhibits store-regulated plasma membrane Ca²⁺/Mn²⁺ permeability in rat thymocytes with an IC₅₀ of 10 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 85473-17-2
Peso molecular 341.28
Fòrmula C₁₇H₂₂Cl₂N₂O
SMILES

ClC1=CC=C(C(Cl)=C1)C(O)(CN2C=NC=C2)CCCCCC
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Alvarez J, et al. Cytochrome P450 may regulate plasma membrane Ca2+ permeability according to the filling state of the intracellular Ca2+ stores. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 1992 Jan 06;6(2):786-92. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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