VL-0395
VL-0395 is a CCK1 selective antagonist with IC50 of 0.197 μM for CCK1 in rat pancreatic acinar cells.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 620167-11-5
- Fòrmula: C25H21N3O4
- Peso molecular:427.45
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
197 nM
Compound: VL-0395
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Displacement of [111In]DTPA-Glu-Gly-[Tyr27(SO3H)]-CCK8 from human CCK1 receptor in A431 cells
Displacement of [111In]DTPA-Glu-Gly-[Tyr27(SO3H)]-CCK8 from human CCK1 receptor in A431 cells
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[PMID: 16610788] |
Chemical Information
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No. CAS 620167-11-5
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Peso molecular 427.45
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Fòrmula C25H21N3O4
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SMILES
O=C(C(CC1=CC=CC=C1)NC(C2=C(NC(C3=CC4=C(N3)C=CC=C4)=O)C=CC=C2)=O)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VL-0395 Related Classifications
HY-118904 Related Classifications
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