VR23-d8
VR23-d8 is the deuterium labeled VR23 (HY-18741). VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC50=1 nM), chymotrypsin-like proteasomes (IC50=50-100 nM), and caspase-like proteasomes (IC50=3 μM).
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- No. CAS: 2733154-83-9
- Fòrmula: C19H8D8ClN5O6S
- Peso molecular:485.93
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Help & FAQs
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 2733154-83-9
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Unlabeled Cas 1624602-30-7
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Peso molecular 485.93
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Fòrmula C19H8D8ClN5O6S
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SMILES
ClC1=CC2=C(C(N3C([2H])(C([2H])(N(C([2H])(C3([2H])[2H])[2H])S(C4=C(C=C(C=C4)[N+]([O-])=O)[N+]([O-])=O)(=O)=O)[2H])[2H])=CC=N2)C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VR23-d8 Related Classifications
HY-W720448 Related Classifications
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