ZW290
Based on 1 Customer Validation
ZW290 is a compound to activate brown adipose tissue (BAT) thermogenic function. ZW290 increases the expression of uncoupling Protein 1 (UCP1) protein and inhibits ATP synthesis in BAT.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.60%
- No. CAS: 2411852-67-8
- Fòrmula: C20H18N2O6S
- Peso molecular:414.43
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Actividad biológica
ZW290 in brown adipose tissue (BAT) induces nonshivering thermogenesis by limiting the oxidation of lipid droplet-derived fatty acids and increasing UCP1 protein levels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Kunming (KM) mice (20 g) keeping under acute cold exposure (-20°C)[1]
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Dosage:25 mg/kg, 50 mg/kg, or 100 mg/kg
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Administration:Oral gavage; once a day; for 7 days
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Result:Notably decreased the size of lipid droplets in BAT and increased the content of mitochondria and the expression of UCP1 in BAT and WAT.
Chemical Information
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No. CAS 2411852-67-8
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Appearance Solid
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Peso molecular 414.43
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Fòrmula C20H18N2O6S
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Color Yellow to brown
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SMILES
O=C1N(C2=CC=C(C=C2)OC)C(N/C1=C\C3=CC(OC)=C(C=C3)OCC(O)=O)=S
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZW290 Related Classifications
HY-148973 Related Classifications
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