GBR-12879 dihydrochloride

Cat. No.: HY-100929 Purity: 95.03%: Data Sheet
COA

SDS
Handling Instructions
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GBR-12879 dihydrochloride is a potent inhibitor of dopamine uptake.

For research use only. We do not sell to patients.

GBR-12879 dihydrochloride Chemical Structure

CAS No. : 67469-45-8

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Other Forms of GBR-12879 dihydrochloride:

GBR-12879 methanesulfonate Get quote

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Dopamine Receptor D₁ Receptor D₂ Receptor D₃ Receptor D₄ Receptor D₅ Receptor

Biological Activity
Purity & Documentation
References
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Description

GBR-12879 dihydrochloride is a potent inhibitor of dopamine uptake^[1].

Molecular Weight

521.47

Formula

C₂₈H₃₂Cl₂F₂N₂O

CAS No.

67469-45-8

Appearance

Solid

Color

White to off-white

SMILES

FC1=CC=C(C(C2=CC=C(F)C=C2)OCCN3CCN(C/C=C/C4=CC=CC=C4)CC3)C=C1.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 83.33 mg/mL (159.80 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9177 mL	9.5883 mL	19.1766 mL
5 mM	0.3835 mL	1.9177 mL	3.8353 mL
10 mM	0.1918 mL	0.9588 mL	1.9177 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.03%

Select Batch:

Data Sheet (266 KB) SDS (252 KB)

COA (247 KB) HNMR (194 KB) LCMS (103 KB)

Handling Instructions (2659 KB)

References

[1]. van der Zee P, et al. Interaction between substituted 1-[2-(diphenylmethoxy)ethyl] piperazines and dopamine receptors. Neuropharmacology. 1985 Dec;24(12):1171-4. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9177 mL	9.5883 mL	19.1766 mL	47.9414 mL
	5 mM	0.3835 mL	1.9177 mL	3.8353 mL	9.5883 mL
	10 mM	0.1918 mL	0.9588 mL	1.9177 mL	4.7941 mL
	15 mM	0.1278 mL	0.6392 mL	1.2784 mL	3.1961 mL
	20 mM	0.0959 mL	0.4794 mL	0.9588 mL	2.3971 mL
	25 mM	0.0767 mL	0.3835 mL	0.7671 mL	1.9177 mL
	30 mM	0.0639 mL	0.3196 mL	0.6392 mL	1.5980 mL
	40 mM	0.0479 mL	0.2397 mL	0.4794 mL	1.1985 mL
	50 mM	0.0384 mL	0.1918 mL	0.3835 mL	0.9588 mL
	60 mM	0.0320 mL	0.1598 mL	0.3196 mL	0.7990 mL
	80 mM	0.0240 mL	0.1199 mL	0.2397 mL	0.5993 mL
	100 mM	0.0192 mL	0.0959 mL	0.1918 mL	0.4794 mL